College football odds: Opening lines for Week 1, biggest college football games of 2021
The first weekend of college football is right around the corner, and we already have betting spreads for most of the games available for Week 1 of the 2021 college football season.
Labor Day Weekend has some quality matchups, including the Georgia Bulldogs and Clemson Tigers doing battle in Charlotte, North Carolina. DJ Uiagalelei steps in for Trevor Lawrence as the starting quarterback for the huge favorites to win a seventh-straight ACC Championship.
Also the calendar will begin with the Alabama Crimson Tide in their second home of Mercedes-Benz Stadium in Atlanta against the Miami Hurricanes. It’s technically a home game for Canes quarterback D’Eriq King, who must be working on a second doctorate degree by now, as well as head coach Manny Diaz. But you can expect most of the fans will be rooting for the Tide to roll as three-score favorites.
Here are the current odds for Week